Advantix vs Frontline

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(Last Updated On: April 17, 2021)

Warmer weather is knocking at the door and calling us out of our homes now that the winter has passed. There is always that change you feel in the air, a change that is drawing you to spend your time outside. And you are not the only one who feels that way. Your pets are also feeling that urge to go out and catch some of that sweet sunlight.

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All of this means that you and your dog will soon take trips to the woods, the lake, the ocean, the mountain, and wide-open fields. There are a couple of downsides to warm weather, and some of them are bugs, insects, and parasites.

Everyone thinks of mosquitoes when they think about bugs and warm weather, but what about ticks? Ticks are much more dangerous than a mosquito because they can spread diseases more quickly.
Luckily, you can apply any kind of bug repellent on your skin, but what about your dog?
It is crucial to protect your dog from parasites such as fleas and ticks. You probably know that there are countless pest repellents for pets, but do you know which one to choose? If you wish to find out, you have come to the right place.

About Advantix

Advantix is formulated to quickly kill off any fleas and ticks that decide to land on your dog. Since one bite from an infected tick can prove fatal, it is vital to protect your dog with a top-quality repellent.
Advantix is capable of stopping fleas from feeding in a span of 5 minutes, and it can kill adult fleas along with the larva in 20 minutes.
Also, this product is capable of not just killing fleas that are already on your dog. It will also kill any fleas in your dog’s surrounding. This means that you won’t have to thoroughly clean all your furniture and home. Advantix is completely water resistant, and it also protects your dog from mosquito and sand fly bites.

About Frontline

Frontline offers great protection for your dog against various insects, bugs, and parasites. This repellent controls and prevents infestations, kills flea larvae, flea eggs, and adult fleas. It also prevents all stages of flea infestation from spreading.
It is a long-lasting, fast-acting and waterproof repellent which can protect your dog from any insects and parasites.


While both of these products are effective and they do what they say, there are some differences between these two that we should get out of the way.

Advantix kills and repels more stuff than Frontline. It kills and repels biting flies, mosquitoes, ticks, fleas, and lice.

By comparison, Frontline is also perfect for killing but not so much for repelling. Frontline won’t be able to repel lice, fleas, and ticks and it won’t do much for protection from biting flies and mosquitoes.

The great thing about Frontline is that it will affect the flea eggs. If your dog already has fleas, then Frontline might be a better choice for you. If not, I would recommend Advantix.

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Side Effects

If you are worried about the side effects your dog might experience from these repellents, you will be glad to hear that side effects are extremely low. If they do appear, the most common side effect is irritation at the spot where products were applied.

But don’t worry, this side effect usually clears up in no time. It won’t leave any permanent marks on your dog.

Also, you will have to be really careful which product you choose if you have more than one pet. Advantix has an ingredient called permethrin which won’t do anything to dogs, but can be lethal for your cat. Never apply Advantix on your cat. The best thing you can do if you have a cat is to avoid using Advantix on your dog altogether.


How long does a dose last?

Both Advantix and Frontline will last for one month.

Should I ‘quarantine’ my dog after applying repellents?

After you apply Advantix, keep your dog dry and don’t let him swim because the product is dangerous for aquatic life. Also, keep all cats away from your dog. If you apply Frontline, just make sure that your dog stays dry for the next 24 hours.

If my dog is pregnant or nursing, can I still use these repellents?

You can freely apply Frontline and Advantix if your dog is pregnant and/or nursing.

Quick Comparison


  • Prevents fleas from feeding within 5 minutes
  • Easy to use, just apply it on the dog once every month or every two weeks for better protection
  • It is completely safe, and you can use it on pregnant dogs and puppies older than 7 weeks
  • Kills and repels ticks
  • It is resistant to water
  • Prevents fleas from biting


  • Prevents and stops infestations
  • Kills flea larvae, adult fleas, and flea eggs
  • Able to kill American dog ticks, brown dog ticks, lone star ticks, and deer ticks which are known to carry and spread Lyme disease
  • Easy to use, apply it once every month

Final Conclusion

Now that you know all there is to know about both of these repellents, let’s try and settle the score which one is better.

If you take everything said above into account, I would say that Advantix is a better choice for your dog. But only if you don’t have a cat!

It is always best to contact your vet before you decide to do anything that might affect the health of your furry friend. The best way to go is to combine one of these products with a repellent collar. This combination is proving to be the absolute best at fighting infestations.

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